In numerous reports to the Malwarebytes support forums since Windows 10 version 2004, the May 2020 Update, was released, users are reporting many problems with MBAM 4.1 installed.
These issues range from random freezes, general slowness, video stuttering, blue screen of death crashes (BSOD), or Windows 10 becoming unresponsive.
[Stress that] not everyone running Windows 10 2004 seems to be affected,
Malwarebytes has released a Windows Beta version 4.1.1.71 in early June that appears to resolve this issue.
Full article with more details: https://www.bleepingcomputer.com/news/microsoft/malwarebytes-causing-performance-issues-in-windows-10-2004/
Malwarebytes acknowledges performance issues on devices running Windows 10 v2004
saying it "seems to be related to conflicts with our Ransomware Protection."
https://forums.malwarebytes.com/topic/261111-performance-issue-with-windows-10-2004
Malwarebytes has just released version 4.1.2.73 (with component update 1.0.972) which should be addressing the Window 10 2004 incompatibility issues.
https://forums.malwarebytes.com/topic/257102-malwarebytes-41/?tab=comments#comment-1391173